Article
Development of genomic phenotype and immunophenotype of acute respiratory distress syndrome using autophagy and metabolism-related genes.
Frontiers in immunology - 1 Jan 2023
Xia Feiping, Chen Hui, Liu Yigao, Huang Lili, Meng Shanshan, Xu Jingyuan, Xie Jianfeng, Wang Guozheng, Guo Fengmei
Abstract excerpt
Background: Distinguishing ARDS phenotypes is of great importance for its precise treatment. In the study, we attempted to ascertain its phenotypes based on metabolic and autophagy-related genes and infiltrated immune cells. Methods: Transcription datasets of ARDS patients were obtained from Gene expression omnibus (GEO), autophagy and metabolic-related genes were from the Human Autophagy Database and the...
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