Article

DMSO-free cryopreservation of hiPSC-derived cardiomyocytes: Low temperature characterization and protocol development

2025-04-14

Abstract excerpt

<title>Abstract</title> <p>Background Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have attracted significant interest for use in disease modeling, drug discovery and potential therapeutic applications. However, conventional hiPSC-CM cryopreservation protocols largely use dimethyl sulfoxide (DMSO) as the cryoprotectant (CPA), which is linked with a loss of post-thaw recovery and functio...

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Literature Corpus work: 0223379b-dc82-510f-8b00-c75d18840c8b
DOI: 10.21203/rs.3.rs-5183739/v1

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