Article

Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes

2016-02-02

Abstract excerpt

Bacterial genomes vary extensively in terms of both gene content and gene sequence – this plasticity hampers the use of traditional SNP-based methods for identifying all genetic associations with phenotypic variation. Here we introduce a computationally scalable and widely applicable statistical method (SEER) for the identification of sequence elements that are significantly enriched in a phenotype of interest. SE...

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Literature Corpus work: 021536d5-77c5-552d-a0de-7c89c1f5a251
DOI: 10.1101/038463

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