Back to search

Article

Mapping cross-domain drivers of Alzheimer’s disease risk through integrated network analysis

2025-10-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Alzheimer’s Disease (AD) is a complex neurodegenerative disorder with numerous known risk factors. Identification of which genetic factors are causal drivers is difficult due to the long disease prodrome in an inaccessible organ. The application of integrative, systems-level approaches are crucial for addressing this complexity. <h4>Methods</h4> Sixteen biological domain...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7de4fea9-d92e-5d56-9893-a19c18c1fdf6
DOI
10.1101/2025.10.16.682921
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Mapping cross-domain drivers of Alzheimer’s disease risk through integrated network analysisDOI 10.1101/2025.10.16.682921
Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domainsSemantic proximity
Genetic and Multi-omic Risk Assessment of Alzheimer’s Disease Implicates Core Associated Biological DomainsSemantic proximity
Unraveling the Genetic Comorbidity Landscape of Alzheimer’s DiseaseSemantic proximity
Decoding the Genetic Comorbidity Network of Alzheimer's DiseaseSemantic proximity
Genetic and Multi-omic Risk Assessment of Alzheimer’s Disease Implicates Core Associated Biological DomainsSemantic proximity
Genetic Networks of Alzheimer’s Disease, Aging and Longevity in HumansSemantic proximity
Toward a Full Understanding of Causal and Modifiable Risk Factors for Alzheimer's Disease by Integrative Phenome-wide Association Studies.Semantic proximity
Genetic Networks of Alzheimer’s Disease, Aging, and Longevity in HumansSemantic proximity
Novel graph theoretic biological pathway network analytics methods for analyzing and discovering Alzheimer’s disease related genesSemantic proximity
Uncovering systems-level molecular similarities between Alzheimer’s and Parkinson’s diseasesSemantic proximity
An Integrated Molecular Atlas of Alzheimer’s DiseaseSemantic proximity
Key Regulators of Alzheimer’s Disease: Network Biology and In-Silico Analysis with AChE and Glutamate InhibitorsSemantic proximity
Select a neighboring publication to make it the new centre.