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Multi-omics analysis reveals coordinated lipid and iron metabolism alterations associated with pathological complete response to neoadjuvant immunochemotherapy in LA OPSCC

2026-08-06

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Neoadjuvant immunochemotherapy (nCIT) is used for locally advanced oropharyngeal and hypopharyngeal squamous cell carcinoma (LA OPSCC), but the biological basis of pathological complete response (PCR) remains unclear. Metabolic reprogramming beyond immune activation may play a critical role. <bold>Methods:</bold> Serum metabolic profiles (iron, ferritin, li...

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Literature Corpus work
01a927f1-2574-55b9-97f8-405ab2b0f5d9
DOI
10.21203/rs.3.rs-10167293/v1
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Multi-omics analysis reveals coordinated lipid and iron metabolism alterations associated with pathological complete response to neoadjuvant immunochemotherapy in LA OPSCCDOI 10.21203/rs.3.rs-10167293/v1
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