Article
Microfluidic Chip for Label-Free Removal of Teratoma-forming Cells from Therapeutic Human Stem Cells
2019-11-04
Abstract excerpt
<h4>ABSTRACT</h4> Teratoma formation remains a safety concern in therapeutic cells derived from human-induced pluripotent stem cells (hiPSCs). Residual Teratoma forming cells are present in small numbers in differentiated hiPSC cultures and yet are of significant roadblock to the manufacturing and clinical translation of stem cell therapies. Rare cells are often difficult to remove with standard flow cytometry or...
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Identifiers and source
- Literature Corpus work
- 017aba43-625a-5dc7-9fe9-13141578fdc4
- DOI
- 10.1101/830588
