Article

Construction of a pH-responsive nanoreactor and its specific inhibition of oral squamous cell carcinoma growth via TME and xCT/GSH/GPX4 axis

2023-10-18

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in oral and maxillofacial region, distinguished by its formidable invasiveness, high incidence of lymph node metastatic, and unfavorable prognosis. Given the current dearth of specific drugs, effectively curtailing its growth, invasion, and metastasis poses a significant challenge. The tumor microenvironment (TME) exhibits mildly acidic conditi...

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Literature Corpus work: 011b3a6f-3aef-5b06-ae51-c1ca362a467d
DOI: 10.21203/rs.3.rs-3422754/v1

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