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Electrostatically Assembled CaO2@MPN-HA Nanoreactors Potentiate Anti-PD-1 Therapy in Thyroid Cancer via Synergistic Ferroptosis and Calcium Overload

2026-01-20

Abstract excerpt

<title>Abstract</title> <p> Immune checkpoint blockade (ICB) therapy has achieved remarkable breakthroughs in clinical cancer treatment; however, its efficacy is often limited by the immunosuppressive characteristics of the tumor microenvironment (TME) and the insufficient infiltration of cytotoxic T lymphocytes. Inducing immunogenic cell death (ICD) to convert “cold tumors” into “hot tumors” is an effective str...

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Literature Corpus work
e99ea735-0543-51b6-ade3-d1cfa024c3de
DOI
10.21203/rs.3.rs-8433282/v1
Open publication

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Electrostatically Assembled CaO2@MPN-HA Nanoreactors Potentiate Anti-PD-1 Therapy in Thyroid Cancer via Synergistic Ferroptosis and Calcium OverloadDOI 10.21203/rs.3.rs-8433282/v1
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