Article

Biodegradable Mesoporous Manganese Carbonate Nanocomposites for LED Light-Driven Cancer Therapy via Enhancing Photodynamic Therapy and Attenuating Survivin Expression

2021-09-01

Abstract excerpt

<title>Abstract</title> <p>Triple-negative breast cancer (TNBC) is one of the most daunting diseases, and low toxicity and efficient approaches are in urgent demand. Herein, we developed degradable mesoporous manganese carbonate nanocubes (MnCO<sub>3</sub> NCs), incorporated with survivin shRNA-expressing plasmid DNA (iSur-pDNA) and riboflavin (Rf), namely MRp NCs, for synergistic TNBC therapy. The MnCO<sub>3</su...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9af7227e-664a-5c86-a9db-229de28bbcf8
DOI: 10.21203/rs.3.rs-847366/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Biodegradable Mesoporous Manganese Carbonate Nanocomposites for LED Light-Driven Cancer Therapy via Enhancing Photodynamic Therapy and Attenuating Survivin ExpressionDOI 10.21203/rs.3.rs-847366/v1Read

Evaluation of the performance of Fe 3 O 4 /MnO 2 hybrid nanozymes with doxorubicin on multicellular structure and their therapeutic management to limit the growth of human breast cancer cellsSemantic proximity Read

A CDDP-Cross-Linked Nanoprodrug for Combination Therapy Based on Dual-Augmented Cascade ReactionsSemantic proximity Read

Mitochondria-Targeted Nanoplatforms For Enhanced Photodynamic Therapy Against Hypoxia TumorSemantic proximity Read

Glucose oxidase virus-based nanoreactors for smart breast cancer therapySemantic proximity Read

High-performance pyrite nano-catalyst driven photothermal/chemodynamic synergistic therapy for OsteosarcomaSemantic proximity Read

An Efficient Magnetic Nanocatalyst Induced Chemo- and Ferroptosis Synergistic Cancer Therapy in Combination with T1-T2 Dual-Mode Magnetic Resonance Imaging through Doxorubicin DeliverySemantic proximity Read

Anti-Tumor Therapy through High ROS Performance induced by Ag Catalase from Boron Cluster with Halloysite Clay NanotubesSemantic proximity Read

A super-assembled synergistically nanoplatform AP@ZIF-8 Pt for hepatocarcinoma therapySemantic proximity Read

Engineered MoS₂ Nanoplatforms for Drug-Enhanced Cancer Phototherapy: From Design Strategies to Translational OpportunitiesSemantic proximity Read

MOF-Based Nanoagent Enables NIR-Triggered Dual Damage to Mitochondria via Synergistically Reinforced Oxidative Stress and Calcium OverloadSemantic proximity Read

Hypoxia-Responsive Nanoreactors to Amplify Oxidative Damage Through Multiple Cascaded Pathways for Promoting Photodynamic/Ferroptosis-Induced ROS Generation and Simultaneously Disrupting Tumor Antioxidant Defense SystemSemantic proximity Read

Applications of Boron cluster Supramolecular Frameworks as Metal-free Chemodynamic Therapy AgentsSemantic proximity Read