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In vivo emergence of ceftazidime-avibactam resistance and loss of hypermucoviscosity in carbapenem-resistant Klebsiella pneumoniae during antibiotics treatment

2022-06-29

Abstract excerpt

<h4>Background: </h4> Ceftazidime-avibactam (CZA) is currently one of the few effective antibiotics for carbapenem-resistant Enterobacteriaceae (CRE). We characterized in vivo evolution of carbapenem and CZA resistance and decreased hypermucoviscosity (Hmv) by analyzing two longitudinal carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) clinical isolates (FK8578, FK8695) from an ICU patient during...

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Literature Corpus work
0100e480-b5ac-5f35-976a-ae777fd980ee
DOI
10.21203/rs.3.rs-1794863/v1
Open publication

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In vivo emergence of ceftazidime-avibactam resistance and loss of hypermucoviscosity in carbapenem-resistant Klebsiella pneumoniae during antibiotics treatmentDOI 10.21203/rs.3.rs-1794863/v1
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