Back to search

Article

Acquisition of Strain-Specific Fragment and Capsular-Biofilm Traits Drives Host Adaptation and Resistance Evolution in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae

2026-04-24

Abstract excerpt

<title>Abstract</title> <p> Background The convergence of hypervirulence and carbapenem resistance in <italic>Klebsiella pneumoniae</italic> has led to the emergence of hypervirulent carbapenem-resistant <italic>K. pneumoniae</italic> (hv-CRKP), posing serious clinical and public health challenges. However, the genetic mechanisms underlying this convergence remain incompletely understood. Results We retros...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e224606f-16e6-59b1-a11e-bcd8c8eb606c
DOI
10.21203/rs.3.rs-8594311/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Acquisition of Strain-Specific Fragment and Capsular-Biofilm Traits Drives Host Adaptation and Resistance Evolution in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniaeDOI 10.21203/rs.3.rs-8594311/v1
Comparative genomic, phenotypic, and clinical characterization of ST11-KL25 and ST11-KL64 hypervirulent carbapenem-resistant Klebsiella pneumoniae in a tertiary hospital, 2020-2023.Semantic proximity
Chasing the landscape for intrahospital transmission and evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniaeSemantic proximity
Infection with Carbapenem-resistant Hypervirulent Klebsiella Pneumoniae: clinical, virulence and molecular epidemiological characteristicsSemantic proximity
Molecular characteristics and pathogenic mechanisms of KPC-3 producing hypervirulent carbapenem-resistant Klebsiella pneumoniae (ST23-K1)Semantic proximity
Distinct and Shared Impacts of Virulence Plasmids on the Phenotype and Transcriptome in Convergent Carbapenem-Resistant and Hypervirulent <i>Klebsiella pneumoniae</i>Semantic proximity
Clonal transmission of a ceftazidime–avibactam-resistant hypervirulent Klebsiella pneumoniae KL64-ST11 strains harboring bla NDM-1 , bla KPC-2 , and ompk36 deletionSemantic proximity
Clinical and Molecular Characteristics of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolates in a Tertiary Hospital in Shanghai, ChinaSemantic proximity
Virulence Plasmid with IroBCDN Deletion Promoted Cross-regional Transmission of ST11-KL64 Carbapenem-resistant Hypervirulent Klebsiella Pneumoniae in central ChinaSemantic proximity
Global emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae driven by an IncFIIK34 KPC-2 plasmidSemantic proximity
Emergence of Dual-Risk <i>Klebsiella pneumoniae</i> : Global Hotspots of Convergence Between Resistance and HypervirulenceSemantic proximity
A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniaeSemantic proximity
Deciphering the Epidemiological Characteristics and Molecular Features of blaKPC–2- or blaNDM–1-Positive Klebsiella pneumoniae Isolates in a Newly Established HospitalSemantic proximity
Select a neighboring publication to make it the new centre.