Article
In vivo evolution to hypermucoviscosity and ceftazidime/avibactam resistance in a liver abscess caused by Klebsiella pneumoniae sequence type 512.
mSphere - 25 Sept 2024
Capitani Valerio, Arcari Gabriele, Ambrosi Cecilia, Scribano Daniela, Ceparano Mariateresa, Polani Riccardo, De Francesco Alice, Raponi Giammarco, Ceccarelli Giancarlo, Villari Paolo, Palamara Anna Teresa, Marzuillo Carolina, Carattoli Alessandra
Abstract excerpt
Carbapenemase-producing Klebsiella pneumoniae represents a major public health issue globally. Isolates with resistance to the newest drugs, like ceftazidime/avibactam (CZA), are increasingly reported. In this study, we analyzed the evolution of KPC-3-producing sequence type (ST) 512 K. pneumoniae strains isolated at three different times (hospitalization days 45, 56, and 78) from the same patient, two of which...
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