Article

Development and Clinical Validation of Global Tau Severity Score in Young- and Late- Onset Alzheimer's Disease Using Florzolotau (18F) PET

2024-02-09

Abstract excerpt

<h4>Background: </h4> Tau-specific positron emission tomography (tau-PET) holds promise in distinguishing Alzheimer's disease (AD) and elucidating the spatial distribution of tau deposition. In particular, the phenotypic differences between the young-onset AD [YOAD] and late-onset AD [LOAD] likely arise from the distinct biological properties of tau proteins to their downstream pathways. This study aimed to establ...

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Literature Corpus work: 00d86eb2-5b92-5817-8545-ec0a5319be60
DOI: 10.21203/rs.3.rs-3932300/v1

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