Article

Generative Chemistry Platform for Small Molecules Targeting RNA: A Case Study for Chemical Optimization

2026-05-12

Abstract excerpt

We introduce the Serna Bio GenAI platform, a generative chemistry and multiparametric optimization platform for the design of RNA-targeting small molecules. Targeting RNA with small molecules has proven historically challenging but offers notable potential upsides, including access to unique mechanisms of action and the ability to target otherwise untargetable genes. We consider a major challenge here to be design...

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Literature Corpus work: 00b6bb33-cc0e-533e-b040-e3e5c8b5a878
DOI: 10.64898/2026.05.08.723908

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