Article

NFIB controls chemosensitivity in small cell lung cancer by suppressing Notch signaling activity

2024-01-17

Abstract excerpt

<h4>Background: </h4> Small cell lung cancer(SCLC) is a highly aggressive malignant tumor type, characterized by universal acquired therapeutic resistance during rapidly recurrence. However, we have a poor understanding of the mechanisms underlying development of resistance. NFIB is a bona fide oncogene in SCLC with effects on proliferation, invasion, and apoptosis inhibition. <h4>Methods: </h4>: The expression o...

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Literature Corpus work: 00b0d4ce-f708-596d-b84b-606d72a8117e
DOI: 10.21203/rs.3.rs-3866018/v1

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