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Longitudinal transcriptional changes reveal genes from the natural killer cell-mediated cytotoxicity pathway as critical players underlying COVID-19 progression

2024-01-05

Abstract excerpt

<h4>ABSTRACT</h4> Patients present a wide range of clinical severities in response SARS-CoV-2 infection, but the underlying molecular and cellular reasons why clinical outcomes vary so greatly within the population remains unknown. Here, we report that negative clinical outcomes in severely ill patients were associated with divergent RNA transcriptome profiles in peripheral immune cells compared with mild cases d...

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Literature Corpus work
0076a9f3-7968-57fd-9baf-511858b80939
DOI
10.1101/2024.01.02.573936
Open publication

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Longitudinal transcriptional changes reveal genes from the natural killer cell-mediated cytotoxicity pathway as critical players underlying COVID-19 progressionDOI 10.1101/2024.01.02.573936
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