Article

Deficiency of IQCH causes male infertility in humans and mice

2023-06-26

Abstract excerpt

IQ motif-containing proteins can be recognized by calmodulin (CaM) and are essential for many biological processes. However, the role of IQ motif-containing proteins in spermatogenesis is largely unknown. In this study, we identified a loss-of-function mutation in the novel gene IQ motif-containing H ( IQCH ) in a Chinese family with male infertility characterized by a cracked flagellar axoneme and abnormal mitoc...

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Literature Corpus work: 0045d4ba-183d-553d-9f83-25d9c9495d4c
DOI: 10.1101/2023.06.23.546221

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