Article
Machine Learning Model Based on Insulin Resistance Metagenes Underpins Genetic Basis of Type 2 Diabetes.
Biomolecules - 24 Feb 2023
Saxena Aditya, Mathur Nitish, Pathak Pooja, Tiwari Pradeep, Mathur Sandeep Kumar
Abstract excerpt
Insulin resistance (IR) is considered the precursor and the key pathophysiological mechanism of type 2 diabetes (T2D) and metabolic syndrome (MetS). However, the pathways that IR shares with T2D are not clearly understood. Meta-analysis of multiple DNA microarray datasets could provide a robust set of metagenes identified across multiple studies. These metagenes would likely include a subset of genes (key...
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