Article
Serum paraoxonase after myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 1999
Ayub A, Mackness M I, Arrol S, Mackness B, Patel J, Durrington P N
Abstract excerpt
HDL has been shown to prevent the oxidative modification of LDL. The antioxidant activity of HDL is believed to reside in its enzymes, particularly paraoxonase. Human serum paraoxonase (PON1) is closely associated with a specific HDL subfraction also containing apoA1 and clusterin. Recently PON1 has been implicated in the pathogenesis of atherosclerosis. We have examined the activity, concentration, and specific...
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