Article
A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1999
Tan L C, Gudgeon N, Annels N E, Hansasuta P, O'Callaghan C A, Rowland-Jones S, McMichael A J, Rickinson A B, Callan M F
Abstract excerpt
EBV is a gammaherpesvirus that can establish both nonproductive (latent) and productive (lytic) infections within the cells of its host. Although T cell responses to EBV latent proteins have been well characterized, little is known about the importance of responses to lytic proteins in long term virus carriers. Here we have compared the frequencies of CD8+ T cells specific for EBV latent and lytic Ags in healthy...
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