Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A PstI polymorphism detects the mutation of serine128 to arginine in CD 62E gene - a risk factor for coronary artery disease.

Journal of biomedical science - 1 Jan 1999

Ye S Q, Usher D, Virgil D, Zhang L Q, Yochim S E, Gupta R

Abstract excerpt

The mutation of serine128 to arginine in the CD 62E gene is a risk factor for coronary artery disease (CAD). We designed a new method to detect this mutation based on the observation that it is due to a transversion of nucleotide A561 to C, which abolishes a PstI recognition site. Two alleles, A and C, are easily typed when genomic DNA is amplified by PCR, digested with PstI, and separated on agarose gels. Among...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Heterozygote

Share to Mutation

Share to Polymorphism, Genetic

Share to Reference Values

Source

Identifiers

PMID: 9933738
DOI: 10.1007/BF02256419

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

A PstI polymorphism detects the mutation of serine128 to arginine in CD 62E gene - a risk factor for coronary artery disease.PMID 9933738Read ↗

A novel CYBA variant, the -675A/T polymorphism, is associated with essential hypertension.Semantic proximity Read ↗

E-selectin S128R polymorphism and severe coronary artery disease in Arabs.Semantic proximity Read ↗

DNA polymorphisms in adhesion molecule genes--a new risk factor for early atherosclerosis.Semantic proximity Read ↗

The K469E polymorphism of the ICAM-1 gene is a risk factor for peripheral arterial occlusive disease.Semantic proximity Read ↗

Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease.Semantic proximity Read ↗

The rs5888 single nucleotide polymorphism in scavenger receptor class B type 1 (SCARB1) gene and the risk of premature coronary artery disease: a case-control study.Semantic proximity Read ↗

A Study of Associations Between rs9349379 (PHACTR1), rs2891168 (CDKN2B-AS), rs11838776 (COL4A2) and rs4880 (SOD2) Polymorphic Variants and Coronary Artery Disease in Iranian Population.Semantic proximity Read ↗

Identification of genetic markers associated with coronary artery disease in Pakistani Pashtun population: A case-control association study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.