Experimental melanin-induced uveitis in the Fischer 344 rat is inhibited by anti-CD4 monoclonal antibody, but not by mannose-6-phosphate.

doi:10.1046/j.1365-2249.1999.00765.x

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Article

Experimental melanin-induced uveitis in the Fischer 344 rat is inhibited by anti-CD4 monoclonal antibody, but not by mannose-6-phosphate.

Clinical and experimental immunology - 1 Jan 1999

Smith J R, Hart P H, Parish C R, Standfield S D, Coster D J, Williams K A

Abstract excerpt

Experimental melanin-induced uveitis (EMIU) is a rodent model of acute anterior uveitis which was described in 1993. We investigated strain susceptibility, and age and gender characteristics of the model, undertook histological and immunohistochemical studies to investigate underlying cellular me...

Topics

Animals
Antibodies, Monoclonal
Autoimmune Diseases
CD4 Antigens
CD4-Positive T-Lymphocytes
Coloring Agents
Female
Male
Mannosephosphates
Melanins
Phenotype
Rats
Rats, Inbred F344
Rats, Inbred Lew
Rats, Inbred Strains
Rats, Inbred WF
Uveitis, Anterior

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Identifiers

PMID: 9933421
DOI: 10.1046/j.1365-2249.1999.00765.x
PMCID: PMC1905186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9933421-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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