Article
HIRA, a DiGeorge syndrome candidate gene, is required for cardiac outflow tract septation.
Circulation research - 5 Feb 1999
Farrell M J, Stadt H, Wallis K T, Scambler P, Hixon R L, Wolfe R, Leatherbury L, Kirby M L
Abstract excerpt
DiGeorge syndrome (DGS) is a congenital disease characterized by defects in organs and tissues that depend on contributions by cell populations derived from neural crest for proper development. A number of candidate genes that lie within the q11 region of chromosome 22 commonly deleted in DGS pat...
Topics
- Animals
- Cardiac Output
- Cell Cycle Proteins
- Chick Embryo
- Chromosome Mapping
- Chromosomes, Human, Pair 22
- DiGeorge Syndrome
- Heart
- Heart Septum
- Histone Chaperones
- Humans
- Neural Crest
- Nuclear Proteins
- Oligonucleotides, Antisense
- Phenotype