Article
Evidence of decreased adhesion between the neural retina and retinal pigmented epithelium of the Mitfvit (vitiligo) mutant mouse.
Cell and tissue research - 1 Jan 1999
Bora N, Defoe D, Smith S B
Abstract excerpt
In order for the retina to function properly, photoreceptor cell outer segments must be in contact with the adjacent retinal pigmented epithelium (RPE). A mouse model homozygous for the vitiligo mutation of the microphthalmia (Mitf) gene manifests disruption of the outer segment/RPE interdigitation and demonstrates progressive loss of the photoreceptor cells. The mouse nevertheless has near normal levels of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.