Article
Evidence of decreased adhesion between the neural retina and retinal pigmented epithelium of the Mitfvit (vitiligo) mutant mouse.
Cell and tissue research - 1 Jan 1999
Bora N, Defoe D, Smith S B
Abstract excerpt
In order for the retina to function properly, photoreceptor cell outer segments must be in contact with the adjacent retinal pigmented epithelium (RPE). A mouse model homozygous for the vitiligo mutation of the microphthalmia (Mitf) gene manifests disruption of the outer segment/RPE interdigitati...
Topics
- Animals
- Cell Adhesion
- DNA-Binding Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Microphthalmia-Associated Transcription Factor
- Microscopy, Electron, Scanning
- Mutation
- Pigment Epithelium of Eye
- Retina
- Retinal Degeneration
- Transcription Factors
- Vitiligo