Article
Electroretinographic assessment of retinal function in microphthalmia mutant mice.
Experimental eye research - 1 Apr 2004
Möller Anna, Eysteinsson Thor, Steingrímsson Eiríkur
Abstract excerpt
The purpose of this study was to examine the effects of mutations in the mouse (Mus musculus) multi-allelic microphthalmia transcription factor (Mitf) gene on retinal function. Mitf mice provide a rare opportunity to assess retinal degeneration caused by defective retinal pigment epithelium (RPE). Electroretinography (ERG) was used to evaluate the functional state of the retina and to determine the role of the...
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