Article
Serotonin receptor variants in disease: new therapeutic opportunities?
Annals of the New York Academy of Sciences - 15 Dec 1998
Peroutka S J
Abstract excerpt
This review describes a novel genetic approach to the assessment of receptor function that is based on association studies of polymorphisms within human genes. The realization that variations within human genes may significantly affect gene function has led to increased use of this approach in recent years. Analysis of polymorphisms within the human 5-HT2A receptor is used as a specific example of the application...
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