Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mutation in the flanking 5'-TA-3' dinucleotide prevents excision of an internal eliminated sequence from the Paramecium tetraurelia genome.

Genetics - 1 Feb 1999

Mayer K M, Forney J D

Abstract excerpt

The germline chromosomes in Paramecium and other ciliated protozoa contain regions of DNA that are excised and eliminated during the development of a new macronuclear genome. Paramecium tetraurelia internal eliminated sequences (IESs) are invariably flanked by a 5'-TA-3' dinucleotide sequence that is part of a larger 8-bp terminal inverted-repeat consensus sequence. Both features, the absolutely conserved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Protozoan
Share to Base Sequence
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 9927454
DOI: 10.1093/genetics/151.2.597
PMCID: PMC1460486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mutation in the flanking 5'-TA-3' dinucleotide prevents excision of an internal eliminated sequence from the Paramecium tetraurelia genome.PMID 9927454Read ↗

A mutation in Paramecium tetraurelia reveals functional and structural features of developmentally excised DNA elements.Semantic proximity Read ↗

Developmentally regulated excision of a 28-base-pair sequence from the Paramecium genome requires flanking DNA.Semantic proximity Read ↗

Massive colonization of protein-coding exons by selfish genetic elements in <i>Paramecium</i> germline genomesSemantic proximity Read ↗

Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: a somatic view of the germline.Semantic proximity Read ↗

A mating-type mutagenesis screen identifies a zinc-finger protein required for specific DNA excision events in Paramecium.Semantic proximity Read ↗

Developmental timing of programmed DNA elimination in <i>Paramecium tetraurelia</i> recapitulates germline transposon evolutionary dynamicsSemantic proximity Read ↗

Internal eliminated sequences interrupting the Oxytricha 81 locus: allelic divergence, conservation, conversions, and possible transposon origins.Semantic proximity Read ↗

N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity Read ↗

N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity Read ↗

Germline-limited transposon remnants foster somatic genome diversificationSemantic proximity Read ↗

Inter-generational nuclear crosstalk links the control of gene expression to programmed genome rearrangements during the <i>Paramecium</i> sexual cycleSemantic proximity Read ↗

A Mendelian mutation affecting mating-type determination also affects developmental genomic rearrangements in Paramecium tetraurelia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.