A mutation in the flanking 5'-TA-3' dinucleotide prevents excision of an internal eliminated sequence from the Paramecium tetraurelia genome.

doi:10.1093/genetics/151.2.597

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Article

A mutation in the flanking 5'-TA-3' dinucleotide prevents excision of an internal eliminated sequence from the Paramecium tetraurelia genome.

Genetics - 1 Feb 1999

Mayer K M, Forney J D

Abstract excerpt

The germline chromosomes in Paramecium and other ciliated protozoa contain regions of DNA that are excised and eliminated during the development of a new macronuclear genome. Paramecium tetraurelia internal eliminated sequences (IESs) are invariably flanked by a 5'-TA-3' dinucleotide sequence tha...

Topics

Animals
Antigens, Protozoan
Base Sequence
Genome, Protozoan
Molecular Sequence Data
Mutation
Paramecium tetraurelia
Sequence Analysis, DNA

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