Article
Population dynamics of HIV-1 inferred from gene sequences.
Genetics - 1 Feb 1999
Grassly N C, Harvey P H, Holmes E C
Abstract excerpt
A method for the estimation of population dynamic history from sequence data is described and used to investigate the past population dynamics of HIV-1 subtypes A and B. Using both gag and env gene alignments the effective population size of each subtype is estimated and found to be surprisingly...
Topics
- Genes, Viral
- Genetic Variation
- Genome, Viral
- HIV-1
- Humans
- Mutation
- Phylogeny
- Population Dynamics
