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Article

Population dynamics of HIV-1 inferred from gene sequences.

Genetics - 1 Feb 1999

Grassly N C, Harvey P H, Holmes E C

Abstract excerpt

A method for the estimation of population dynamic history from sequence data is described and used to investigate the past population dynamics of HIV-1 subtypes A and B. Using both gag and env gene alignments the effective population size of each subtype is estimated and found to be surprisingly small. This may be a result of the selective sweep of mutations through the population, or may indicate an important...

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Identifiers

PMID: 9927440
DOI: 10.1093/genetics/151.2.427
PMCID: PMC1460489

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Source receipt: pubmed, retrieved 7 Sept 2026.

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