Article
A decision rule for quantitative trait locus detection under the extended Bayesian LASSO model.
Genetics - 1 Dec 2012
Mutshinda Crispin M, Sillanpää Mikko J
Abstract excerpt
Bayesian shrinkage analysis is arguably the state-of-the-art technique for large-scale multiple quantitative trait locus (QTL) mapping. However, when the shrinkage model does not involve indicator variables for marker inclusion, QTL detection remains heavily dependent on significance thresholds derived from phenotype permutation under the null hypothesis of no phenotype-to-genotype association. This approach is...
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