Article
Specific inhibition of Elm1 kinase activity reveals functions required for early G1 events.
Molecular and cellular biology - 1 Sept 2003
Sreenivasan Aparna, Bishop Anthony C, Shokat Kevan M, Kellogg Douglas R
Abstract excerpt
In budding yeast, the Elm1 kinase is required for coordination of cell growth and cell division at G(2)/M. Elm1 is also required for efficient cytokinesis and for regulation of Swe1, the budding yeast homolog of the Wee1 kinase. To further characterize Elm1 function, we engineered an ELM1 allele that can be rapidly and selectively inhibited in vivo. We found that inhibition of Elm1 kinase activity during G(2)...
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