Article
A branching non-linear autoregressive model for the transmission of the fragile X dynamic repeat mutation.
Annals of human genetics - 1 Jul 1998
Huggins R M, Loesch D Z, Sherman S L
Abstract excerpt
A non-linear time series version of a model for the transmission of fragile X previously described in Ashley & Sherman (1995) is developed. The model retains the biological features of the Ashley/Sherman model but is easier to generalize and in particular allows the inclusion of covariates such a...
Topics
- Female
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Haplotypes
- Humans
- Male
- Models, Genetic
- Mutation
- Nerve Tissue Proteins
- RNA-Binding Proteins
- Trinucleotide Repeats
- X Chromosome