Article
Wright-Fisher diffusion bridges.
Theoretical population biology - 1 Jul 2018
Griffiths Robert C, Jenkins Paul A, Spanò Dario
Abstract excerpt
The trajectory of the frequency of an allele which begins at x at time 0 and is known to have frequency z at time T can be modelled by the bridge process of the Wright-Fisher diffusion. Bridges when x=z=0 are particularly interesting because they model the trajectory of the frequency of an allele which appears at a time, then is lost by random drift or mutation after a time T. The coalescent genealogy back in...
Topics
- Algorithms
- Alleles
- Bayes Theorem
- Computer Simulation
- Gene Frequency
- Genealogy and Heraldry
- Genetic Drift
- Genetics, Population
- Humans
- Models, Genetic
- Mutation