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Article

Hierarchical Bayes model for random haplotype and family effects in the transmission of fragile-X.

Genetic epidemiology - 1 May 2004

Huggins R M, Loesch D Z, Qian G Q, Bui Q M, Mitchell R J, Dobson M, Taylor A K

Abstract excerpt

A model for the transmission of the CGG repeat sequence associated with the fragile-X dynamic mutation in the FMR1 gene is developed. The model incorporates both haplotype and family effects on the expansion rate of the sequence. The resulting random effects model is fitted to new data, using computer-intensive Markov chain Monte Carlo methods. The results demonstrate both the FRAXAC1-DXS458 haplotype and family...

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Identifiers

PMID: 15095389
DOI: 10.1002/gepi.10316

Genes

FMR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hierarchical Bayes model for random haplotype and family effects in the transmission of fragile-X.PMID 15095389Read ↗

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