Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

aHIF: a Natural Antisense Transcript Overexpressed in Human Renal Cancer and During Hypoxia

20 Jan 1999

Abstract excerpt

BACKGROUND: Nonpapillary renal carcinoma is the predominant form of human kidney cancer and represents a distinct disease entity, morphologically and molecularly, from papillary renal carcinoma. We have discovered a natural antisense transcript that is complementary to the 3' untranslated region of hypoxia inducible factor alpha (HIF1alpha) messenger RNA (mRNA) and is strikingly overexpressed specifically in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer, Hypoxia, and Metabolism
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9923855
DOI: 10.1093/jnci/91.2.143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

aHIF: a Natural Antisense Transcript Overexpressed in Human Renal Cancer and During HypoxiaPMID 9923855Read ↗

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia.Semantic proximity Read ↗

An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma.Semantic proximity Read ↗

EAF2 Suppresses Hypoxia-Induced Factor 1α Transcriptional Activity by Disrupting Its Interaction with Coactivator CBP/p300Semantic proximity Read ↗

A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

Expression and Characterization of Hypoxia-Inducible Factor (HIF)-3α in Human Kidney: Suppression of HIF-Mediated Gene Expression by HIF-3αSemantic proximity Read ↗

Identification of target genes of the transcription factor HNF1β and HNF1α in a human embryonic kidney cell lineSemantic proximity Read ↗

Clinical implications of hypoxia inducible factor in renal cell carcinomaSemantic proximity Read ↗

More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing.Semantic proximity Read ↗

Identification of Alternative Spliced Variants of Human Hypoxia-inducible Factor-1αSemantic proximity Read ↗

Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reactionSemantic proximity Read ↗

Fibronectin 1 mRNA expression correlates with advanced disease in renal cancerSemantic proximity Read ↗

The Heme Oxygenase-1 Protein Is Overexpressed in Human Renal Cancer Cells following Activation of the Ras-Raf-ERK Pathway and Mediates Anti-Apoptotic SignalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.