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Article

Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke.

Circulation - 26 Jan 1999

Zee R Y, Ridker P M, Stampfer M J, Hennekens C H, Lindpaintner K

Abstract excerpt

BACKGROUND: The D/I polymorphism of the ACE gene has been studied in relation to a variety of cardiovascular disorders, including stroke. A number of small studies have been conducted, with inconsistent results. We investigated the association between ACE genotype and the incidence of stroke in a large, prospective, matched case-control sample from the Physicians' Health Study. METHODS AND RESULTS: In the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9918518
DOI: 10.1161/01.cir.99.3.340

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke.PMID 9918518Read ↗

A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease.Semantic proximity Read ↗

ACE gene polymorphism: ischemic heart disease and longevity in 10,150 individuals. A case-referent and retrospective cohort study based on the Copenhagen City Heart Study.Semantic proximity Read ↗

Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease.Semantic proximity Read ↗

Lack of association between angiotensin converting enzyme gene insertion/deletion polymorphism and stroke.Semantic proximity Read ↗

Lack of an association between angiotensin-converting enzyme gene insertion/deletion polymorphism and ischaemic stroke.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism and cerebrovascular disease.Semantic proximity Read ↗

Association between the ACE I/D polymorphism and risk of ischemic stroke: an updated meta-analysis of 47,026 subjects from 105 case-control studies.Semantic proximity Read ↗

Molecular approach to assessing the genetic risk of cerebral infarction: deletion polymorphism in the gene encoding angiotensin 1-converting enzyme.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism has no effect on the risk of atherosclerotic stroke or hypertension.Semantic proximity Read ↗

Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators.Semantic proximity Read ↗

[Investigation of insertion/deletion polymorphism of the ACE gene in stroke patients].Semantic proximity Read ↗

Angiotensin-converting enzyme gene polymorphism is associated with myocardial infarction but not with development of coronary stenosis.Semantic proximity Read ↗

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