Article
ACE gene polymorphism: ischemic heart disease and longevity in 10,150 individuals. A case-referent and retrospective cohort study based on the Copenhagen City Heart Study.
Circulation - 20 May 1997
Agerholm-Larsen B, Nordestgaard B G, Steffensen R, Sørensen T I, Jensen G, Tybjaerg-Hansen A
Abstract excerpt
BACKGROUND: Homozygosity for the deletion allele (D) of the angiotensin-converting enzyme (ACE) gene insertion-deletion polymorphism has been suggested to be a potent risk factor for myocardial infarction. With one exception, the samples studied so far have been small and/or ethnically heterogene...
Topics
- Adult
- Aged
- Aged, 80 and over
- Aging
- Alleles
- Case-Control Studies
- Cohort Studies
- Female
- Genes
- Genotype
- Humans
- Longevity
- Male
- Middle Aged
- Myocardial Ischemia
- Peptidyl-Dipeptidase A
- Phenotype
- Polymorphism, Genetic