Article
ACE gene polymorphism: ischemic heart disease and longevity in 10,150 individuals. A case-referent and retrospective cohort study based on the Copenhagen City Heart Study.
Circulation - 20 May 1997
Agerholm-Larsen B, Nordestgaard B G, Steffensen R, Sørensen T I, Jensen G, Tybjaerg-Hansen A
Abstract excerpt
BACKGROUND: Homozygosity for the deletion allele (D) of the angiotensin-converting enzyme (ACE) gene insertion-deletion polymorphism has been suggested to be a potent risk factor for myocardial infarction. With one exception, the samples studied so far have been small and/or ethnically heterogeneous, and most investigators have studied men only. METHODS AND RESULTS: We investigated the association between ACE...
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