Article
Angiotensin-converting enzyme gene polymorphism is associated with myocardial infarction but not with development of coronary stenosis.
Circulation - 15 Apr 1995
Ludwig E, Corneli P S, Anderson J L, Marshall H W, Lalouel J M, Ward R H
Abstract excerpt
BACKGROUND: Although both genetic and nongenetic factors contribute to the pathogenesis of coronary artery disease, the identification of specific genetic lesions has lagged behind the identification of critical environmental risk factors. A reported association between myocardial infarction (MI) and the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene in European men suggests...
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