Membrane assembly of the Escherichia coli outer membrane protein OmpA: exploring sequence constraints on transmembrane beta-strands.

Abstract excerpt

The eight-stranded antiparallel beta-barrel domain of the OmpA protein from Escherichia coli serves as a paradigm for the study of membrane assembly of integral beta-structured membrane proteins. Previous studies have shown that neither the periplasmic turns nor the surface-exposed loops contain...

Topics

• Amino Acid Sequence
• Bacterial Outer Membrane Proteins
• Base Sequence
• DNA Primers
• Escherichia coli
• Genes, Bacterial
• Lipid Bilayers
• Molecular Sequence Data
• Mutation
• Protein Structure, Secondary