Membrane protein assembly: genetic, evolutionary and medical perspectives.

doi:10.1146/annurev.ge.29.120195.001023

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Article

Membrane protein assembly: genetic, evolutionary and medical perspectives.

Annual review of genetics - 1 Jan 1995

Manoil C, Traxler B

Abstract excerpt

Lipid bilayers are delicate structures that are easily disrupted by a variety of amphipathic molecules. Yet the viability of a cell requires the continued assembly of large amphipathic proteins within its membranes without damage. The need to minimize bilayer disruption may account for a number o...

Topics

Biological Evolution
Disease
Humans
Lipid Bilayers
Membrane Proteins
Models, Molecular
Mutation
Protein Conformation
Protein Folding
Toxicity Tests

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