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Article

Prevalence of recurring BRCA mutations among Ashkenazi Jewish women with breast cancer.

Genetic testing - 1 Jan 1997

Robson M, Dabney M K, Rosenthal G, Ludwig S, Seltzer M H, Gilewski T, Haas B, Osborne M, Norton L, Gilbert F, Offit K

Abstract excerpt

The BRCA1 mutations 185delAG and 5382insC and the BRCA2 mutation 6174delT have been detected in a significant proportion of Ashkenazi Jewish women with early-onset breast cancer. A group of 236 Jewish women with breast cancer was screened for the presence of these alterations. Mutations were detected in 25.0% (59/236). Among women with breast cancer diagnosed at or before the age of 45, the prevalence of these...

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Source

Identifiers

PMID: 10464625
DOI: 10.1089/gte.1997.1.47

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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