Article
Bivariate familial correlation analysis of quantitative traits by use of estimating equations: application to a familial analysis of the insulin resistance syndrome.
Genetic epidemiology - 1 Jan 1999
Trégouët D A, Herbeth B, Juhan-Vague I, Siest G, Ducimetière P, Tiret L
Abstract excerpt
Familial correlation analysis involving two traits may give a better insight into the etiology of multifactorial syndromes than familial analysis focused on single traits. Significant cross-trait correlations between biological relatives but not between spouses suggest that the two traits share c...
Topics
- Algorithms
- Body Mass Index
- Cholesterol, LDL
- Cohort Studies
- Female
- Humans
- Insulin
- Insulin Resistance
- Likelihood Functions
- Male
- Models, Genetic
- Models, Statistical
- Nuclear Family
- Phenotype
- Syndrome
- Triglycerides