Article
Using simultaneous equation modeling for defining complex phenotypes.
BMC genetics - 31 Dec 2003
King Terri M
Abstract excerpt
BACKGROUND: Interactions between multiple biological phenotypes are difficult to model. Simultaneous equation modelling (SEM), as used in econometric modelling, may prove an effective tool for this problem. Generalized linear models were used to derive the structural equations defining the interactions between cholesterol, glucose, triglycerides and high-density lipoprotein cholesterol (HDL-C). These structural...
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