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Article

Angiotensinogen Thr235 variant is associated with abnormal physiologic change of the uterine spiral arteries in first-trimester decidua.

American journal of obstetrics and gynecology - 1 Jan 1999

Morgan T, Craven C, Lalouel J M, Ward K

Abstract excerpt

OBJECTIVE: The angiotensinogen Thr235 polymorphism associated with preeclampsia is tightly linked to a mutation in the angiotensinogen promoter A(-6), which may lead to elevated expression in decidual spiral arteries. We hypothesize that locally elevated angiotensin II levels play a role in failed physiologic change leading to preeclampsia. Our objective was to determine whether spiral artery morphologic...

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PMID: 9914585
DOI: 10.1016/s0002-9378(99)70156-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Angiotensinogen Thr235 variant is associated with abnormal physiologic change of the uterine spiral arteries in first-trimester decidua.PMID 9914585Read ↗

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Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women.Semantic proximity Read ↗

Definitive Molecular Evidence of Renin-Angiotensin System in Human Uterine Decidual CellsSemantic proximity Read ↗

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