Article
Preeclampsia risk and angiotensinogen polymorphisms M235T and AGT -217 in African American and Caucasian women.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Sept 2008
Jenkins Laura D, Powers Robert W, Cooper Mary, Gallaher Marcia J, Markovic Nina, Ferrell Robert, Ness Roberta B, Roberts James M
Abstract excerpt
INTRODUCTION: Genetic variants of the angiotensinogen gene have been linked to both hypertension and preeclampsia. The M235T polymorphism is more common in hypertension and preeclampsia in some populations. A polymorphism in the angiotensinogen basal promoter region of AGT -217 is more common in African Americans with hypertension. The authors investigated the frequency of M235T and AGT -217 in Caucasian and...
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