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Failure of physiological transformation and spiral artery atherosis: their roles in preeclampsia

21 Sept 2020

Abstract excerpt

Physiological transformation with remodeling of the uteroplacental spiral arteries is key to a successful placentation and normal placental function. It is an intricate process that involves, but is not restricted to, complex interactions between maternal decidual immune cells and invasive trophoblasts in the uterine wall. In normal pregnancy, the smooth muscle cells of the arterial tunica media of uteroplacental...

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PMID: 32971013
DOI: 10.1016/j.ajog.2020.09.026

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