Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast.

doi:10.1007/s004380050913

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Article

Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast.

Molecular & general genetics : MGG - 1 Dec 1998

Verkade H M, O'Connell M J

Abstract excerpt

A checkpoint responding to DNA damage in G2 results in a delay in the onset of mitosis through inhibition of p34cdc2 kinase activity via maintenance of inhibitory tyrosine phosphorylation. Genetic analyses of this checkpoint in fission yeast have identified single alleles of several genes, sugges...

Topics

Cell Cycle
DNA Damage
DNA-Binding Proteins
Fungal Proteins
Genes, Fungal
Methyl Methanesulfonate
Mutation
S Phase
Schizosaccharomyces
Schizosaccharomyces pombe Proteins
Sequence Analysis, DNA
Transglutaminases
Ultraviolet Rays

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