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Article

Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast.

Molecular & general genetics : MGG - 1 Dec 1998

Verkade H M, O'Connell M J

Abstract excerpt

A checkpoint responding to DNA damage in G2 results in a delay in the onset of mitosis through inhibition of p34cdc2 kinase activity via maintenance of inhibitory tyrosine phosphorylation. Genetic analyses of this checkpoint in fission yeast have identified single alleles of several genes, suggesting these screens are not yet saturating, and hence further genes await identification. To fully understand the...

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Identifiers

PMID: 9894912
DOI: 10.1007/s004380050913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast.PMID 9894912Read ↗

Fission yeast cut5+, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4+.Semantic proximity Read ↗

Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.Semantic proximity Read ↗

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Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe.Semantic proximity Read ↗

A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints.Semantic proximity Read ↗

The DNA damage checkpoint: A tale from budding yeastSemantic proximity Read ↗

A screen for Schizosaccharomyces pombe mutants defective in rereplication identifies new alleles of rad4+, cut9+ and psf2+.Semantic proximity Read ↗

Induction of a G1-S checkpoint in fission yeast.Semantic proximity Read ↗

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The Saccharomyces cerevisiae F-box protein Dia2 is a mediator of S-phase checkpoint recovery from DNA damage.Semantic proximity Read ↗

Elevated Levels of the Polo Kinase Cdc5 Override the Mec1/ATR Checkpoint in Budding Yeast by Acting at Different Steps of the Signaling PathwaySemantic proximity Read ↗

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe.Semantic proximity Read ↗

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