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Article

Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.

Molecular & general genetics : MGG - 1 Jul 1997

McFarlane R J, Carr A M, Price C

Abstract excerpt

Mutation of the essential Schizosaccharomyces pombe rad4/cut5 gene causes sensitivity to UV and ionising radiation at the permissive temperature whilst at the restrictive temperature cells fail to undergo DNA replication but still attempt mitosis owing to a defective S-phase checkpoint response. Many mutations in genes encoding DNA replication proteins also abolish checkpoint responses, possibly because the...

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PMID: 9268024
DOI: 10.1007/s004380050504

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Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.PMID 9268024Read ↗

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Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe.Semantic proximity Read ↗

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A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints.Semantic proximity Read ↗

The Schizosaccharomyces pombe S-phase checkpoint differentiates between different types of DNA damage.Semantic proximity Read ↗

A screen for Schizosaccharomyces pombe mutants defective in rereplication identifies new alleles of rad4+, cut9+ and psf2+.Semantic proximity Read ↗

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