Functional activity of 3beta-hydroxysteroid dehydrogenase/isomerase.

doi:10.3109/07435809809032644

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Article

Functional activity of 3beta-hydroxysteroid dehydrogenase/isomerase.

Endocrine research - 1 Jan 2000

Mason J I, Naville D, Evans B W, Thomas J L

Abstract excerpt

3Beta-hydroxysteroid dehydrogenase/steroid delta5-isomerase (3beta-HSD/isomerase) was expressed by baculovirus in Spodoptera fungiperda (Sf9) insect cells from cDNA sequences encoding the human wild-type I (placental) enzyme and the human type I mutant- Y253F. The wild-type and Y253F enzymes were...

Topics

Animals
Cell Line
Enzyme Activation
Humans
Multienzyme Complexes
Mutation
NAD
Nandrolone
Progesterone Reductase
Spectrophotometry, Ultraviolet
Spodoptera
Steroid Isomerases

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