Article
Microsatellite alterations and TP53 mutations in plasma DNA of small-cell lung cancer patients: follow-up study and prognostic significance.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Sept 2000
Gonzalez R, Silva J M, Sanchez A, Dominguez G, Garcia J M, Chen X Q, Stroun M, Provencio M, España P, Anker P, Bonilla F
Abstract excerpt
BACKGROUND: Small-cell lung cancer (SCLC), one of the major types of lung cancer, is associated with many different somatic molecular genetic changes. These alterations, observed in tumor DNA, have also been identified in the plasma DNA of patients. We undertook the present study to make a prospective investigation into the correlation between abnormal plasma DNA and patient survival. PATIENTS AND METHODS:...
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