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Article

Preferred CDRH3 lengths for antibodies with defined specificities.

1 Dec 1998

Abstract excerpt

The third complementarity determining regions of heavy chain variable regions (CDRH3) confer the fine specificities of antibodies. The CDRH3 length distribution of all human or all mouse antibodies appears to be more or less random, with the human distribution having a wider spread. Since the Kabat database of aligned amino and nucleotide sequences of proteins of immunological interest has grown at least 4 times...

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Identifiers

PMID: 9885900
DOI: 10.1093/intimm/10.12.1801

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